Flexifen 10mg | 10pcs | Baclofen | Muscle Spasm | ePharma
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Flexifen 10mg Tablet

Generic: Baclofen

Type: Tablet

Pack Size: 10 Pcs

Flexifen 10mg Tablet is prescribed for the management of muscle spasticity, which is characterized by stiffness and tightness in the muscles. This condition can be associated with various underlying causes, including multiple sclerosis, brain or spinal cord injuries, and spinal cord diseases. 


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✅ Description:

Flexifen 10mg Tablet is an anti-spastic agent and muscle relaxer used to treat muscle symptoms caused by conditions such as multiple sclerosis or spinal cord lesions. It can alleviate pain, muscle spasms, and stiffness associated with these conditions. However, Flexifen 10mg Tablet should not be used by individuals under the age of 12, those with allergies to the medication, or breastfeeding mothers. Alcohol consumption should be avoided while taking this medication, as it can temporarily reduce muscle tone and affect balance and motor skills.

This medication is not considered safe during pregnancy, and individuals with kidney disease, a history of stroke or blood clots, epilepsy, seizure disorders, or those taking narcotic medications should consult their doctor before using Flexifen 10mg Tablet.

Possible side effects may include ringing or buzzing in the ears, skin rashes, dizziness, muscle weakness, constipation, mood changes, confusion, nausea, vomiting, headache, and difficult or painful urination.

Patients should follow their doctor's instructions carefully, take the medication as prescribed, and not discontinue it without consulting their healthcare provider. Abrupt discontinuation can lead to withdrawal symptoms such as seizures and hallucinations. If discontinuation is necessary, the doctor may recommend gradually reducing the dose.

Patients should also avoid taking other prescription or over-the-counter sleep-inducing drugs, sedatives, or antispasmodics without consulting their prescriber. Some common side effects like drowsiness, lethargy, or dizziness may occur temporarily, so caution should be exercised when driving or engaging in activities requiring alertness until the individual's response to the medication is known. Eating frequent small meals or using lozenges may help reduce gastrointestinal upset. Any unresolved insomnia, painful urination, changes in urinary patterns, constipation, or persistent confusion should be reported to the doctor.

The uses and effects of the medicine may vary from person to person, so it is advisable to consult a rheumatologist before using Flexifen 10mg Tablet.

Safety Advices


Alcohol
UNSAFE

Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration.


Pregnancy
CONSULT YOUR DOCTOR

Flexifen 10mg Tablet is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor to understand the benefits and potential risks before taking this medicine. 


Breastfeeding
CONSULT YOUR DOCTOR

Consult your doctor before taking  Flexifen 10mg Tablet; your doctor will decide whether  Flexifen 10mg Tablet can be taken by breastfeeding mothers or not.


Driving
CAUTION

Avoid activities that need mental alertness like driving and operating machinery. 


Kidney
CONSULT YOUR DOCTOR

Dose adjustments might be necessary for patients with kidney impairment. Talk to your doctor if you have kidney problems or any related concerns.


Liver
CONSULT YOUR DOCTOR

Patients with liver impairment may require dose adjustments. Consult your doctor if you have liver issues or any concerns about this.

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✔️ Uses of Flexifen 10mg Tablet
  • Muscle Spasm
✔️ How does Flexifen 10mg Tablet work?

Flexifen 10mg Tablet works by reducing or blocking the activity of certain nerves within a part of the brain that controls the contraction and relaxation of muscles, improving the movement of muscles and helping them relax.

✔️ Side Effects of Flexifen 10mg Tablet
  • Dry mouth
  • Sleepiness
  • Weakness
  • Dizziness
  • Headache
  • Nausea
  • Muscle pain
✔️ Quick Suggestions:
  • Regular exercise, such as jogging and walking, promotes muscle stretching, reducing the risk of spasms, tears, and sprains. Massages can also be beneficial.
  • Maintain a comfortable temperature environment, avoiding extremes of cold and heat, and opt for loose-fitting clothing.
  • Adequate rest and sleep are essential. Change your position every two hours to prevent pressure sores.
  • Hot or cold therapy can be effective for treating muscle spasms. Apply an ice pack or hot pack to the affected muscle for 15-20 minutes.
  • It's important to follow your doctor's advice and undergo regular blood tests to monitor liver function.
  • If you have surgery requiring general anesthesia, inform your doctor that you are taking Flexifen 10mg Tablet.
  • If you experience mood swings, depression, or have suicidal thoughts, seek immediate medical attention and consult your doctor.
✔️ Muscle Spasm:

Muscle spasms are characterized by sudden, involuntary contractions of muscles, often resulting in pain and discomfort. These spasms can occur when nerve impulses controlling muscle movements are disrupted. Common symptoms of muscle spasms include:

  • Muscle tightness
  • Joint stiffness
  • Unusual posture
  • Difficulty in moving
  • Pain in affected muscles and joints

Muscle spasms can be triggered by various factors such as fatigue, stress, extreme temperatures (both hot and cold), infections, and wearing tight clothing.

The treatment of muscle spasms typically involves the use of muscle relaxants and exercise:

Muscle Relaxants: These medications work by sedating the muscles, helping to inhibit painful contractions.

Exercise: Regular exercise, including stretching exercises, can help prevent muscle spasms. Stretching exercises promote muscle flexibility, reducing the likelihood of spasms, tears, and sprains.

✔️ Pharmacology

Baclofen works by activating GABAB receptors in the spinal cord, which inhibits both monosynaptic and polysynaptic reflexes. This action blocks the release of neurotransmitters like glutamate and aspartate. Additionally, Baclofen can lead to central nervous system (CNS) depression by acting at intraspinal sites. It also has an antinociceptive (pain-relieving) effect.

✔️ Dosage & Administration of Flexifen 10mg Tablet

Adult Dose for Spasticity:

  • Initially, start with 5 mg three times a day (tid) for 3 days.
  • Increase to 10 mg tid for the next 3 days.
  • Continue increasing in similar increments and intervals until either a total of 20 mg tid is reached or until the desired effect is achieved.
  • The maximum daily dose should not exceed 80 mg.
  • For elderly individuals, start with lower doses.

Child Dose for Spasticity:

  • The recommended dose for children with spasticity is 0.75-2 mg/kg daily.
  • You may initiate treatment with 2.5 mg four times daily and gradually increase the dose every 3 days until the desired effect is achieved.
  • Maintenance doses are as follows:
    • For children aged 6-10 years: 30-60 mg daily
    • For children aged 2-6 years: 20-30 mg daily
    • For children aged 12 months to 2 years: 10-20 mg daily
  • The maximum dose for children over 10 years of age is 2.5 mg/kg daily.

Renal Dose:

  • Individuals with renal impairment may require a dose reduction. It's essential to consult with a healthcare professional to determine the appropriate dosage adjustment based on the degree of renal impairment.
✔️ Interaction

Drug-Drug Interactions: Flexifen 10mg Tablet can potentially interact with several medications, including:

  • Painkillers such as hydrocodone, methadone, acetaminophen, ibuprofen, morphine, fentanyl, and tramadol.
  • Opiate antagonists like naloxone.
  • Other muscle relaxants, such as tizanidine.
  • Medications used to treat mood disorders, including lithium and amitriptyline.
  • Calcium channel blockers like diltiazem.
  • Drugs used in the management of Parkinson's disease, such as levodopa and carbidopa.
  • Antihistamines like promethazine.
  • Sedative medications, including temazepam.
  • Anti-convulsants like carbamazepine.

Drug-Food Interactions: It's advisable to avoid alcohol consumption while taking Flexifen 10mg Tablet, as it can intensify drowsiness, sleepiness, and difficulties in concentration.

Drug-Disease Interactions: Inform your doctor if you have specific medical conditions, including kidney dysfunction, seizures (fits), psychosis (a severe mental disorder characterized by impaired thoughts and emotions), or autonomic dysreflexia (a condition often associated with spinal cord injuries). These conditions may require special consideration when taking Flexifen 10mg Tablet, and your doctor can adjust your treatment accordingly.

✔️ Contraindications
  • If you are allergic to baclofen or any other ingredients of the Flexifen 10mg Tablet.
  • If you had a stomach ulcer.
✔️ Pregnancy & Lactation

Baclofen is classified as pregnancy category B3. While it can cross the placental barrier, its safe use during pregnancy has not been definitively established. The potential benefits should be weighed against the potential risks, and its use during pregnancy should be based on the physician's judgment. Baclofen is excreted in breast milk, but available evidence suggests that the amounts are small and unlikely to harm the infant.

✔️ Precautions & Warnings

Several precautions should be observed when using Baclofen, including careful dosage adjustment in patients with impaired renal function or undergoing chronic hemodialysis. Patients with psychiatric disorders, epilepsy, or a history of these conditions should be closely monitored as exacerbations may occur. Baclofen may lower the seizure threshold, potentially causing seizures upon discontinuation or in cases of overdose. Caution is advised in individuals with peptic ulcers, cerebrovascular diseases, or hepatic, renal, or respiratory failure. Respiratory and cardiovascular function should be closely monitored, especially in patients with cardiopulmonary or respiratory muscle weakness. Baclofen may lead to improved neurogenic bladder emptying, but acute urinary retention can occur in individuals with preexisting sphincter hypertonia.

✔️ Storage Conditions
  • Flexifen 10mg Tablet should be stored at room temperature, protected from moisture and heat.
  • Keep them out of the reach and sight of children and pets.
  • Do not use expired medicines. Discard off the unused medicine appropriately. Do not flush the medicine into the sink.
Frequently Asked Questions (FAQ)

Yes

Flexifen 10mg Tablet is used to treat muscle spasms caused due to various conditions or injuries. It is a condition where your muscle stiffens or tightens.

It's important to avoid using Flexifen 10mg Tablet when muscle tone is necessary for safe balance and movement during specific activities. Reduced muscle tone in certain situations can be unsafe. Additionally, alcohol consumption should be avoided while taking Baclof-10 Tablet 10's to prevent potential side effects. It's also advisable to refrain from driving or engaging in activities that require alertness until you understand how Baclof-10 Tablet 10's affects you, as it may impair your reactions.
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Check our pricing section for Flexifen 10mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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